I never once thought about it before but how do they select a target antigen for what is effectively a human cell? Maybe they could take a similar approach to Rabies or Prion Disease.
BioNTech is doing something similar. Their approach (and likely also Moderna’s approach) works by first identifying mutations in protein coding genes in the cancer cells. Then, they target the resulting mutated protein (that is distinct from the same protein in non-cancer calls) with their vaccines.
I never once thought about it before but how do they select a target antigen for what is effectively a human cell? Maybe they could take a similar approach to Rabies or Prion Disease.
BioNTech is doing something similar. Their approach (and likely also Moderna’s approach) works by first identifying mutations in protein coding genes in the cancer cells. Then, they target the resulting mutated protein (that is distinct from the same protein in non-cancer calls) with their vaccines.