"Larian has been an incredible partner, and together we are proud of the success of Baldur’s Gate 3. Watch this space for more on some awesome D&D games we are bringing to life through Hasbro’s studios and our network of licensing partners. We have an unbeatable library of toy and game brands and many fantastic partners around the world,” Hasbro’s spokesperson said.
Honestly adhering so closely to 5E means it inherits some of the same problems that the tabletop game has.
Many spells are objectively bad or have very narrow use cases. Powerful enemies are immune to so many status effects that it limits the options for characters that aren’t mostly focused on dealing damage. Dual wielding is ineffective compared to just carrying around the biggest great sword you can find. Etc.
At least if you already know these quirks then you can work around them, but going back to play Divinity OS2 I think that Larian will be just fine without the D&D system/setting.